From: Mutational profile of pfdhfr, pfdhps, pfmdr1, pfcrt and pfk13 genes of P. falciparum associated with resistance to different antimalarial drugs in Osun state, southwestern Nigeria
Codon mutation
No. of isolates (n)
Frequency (%)
Genes
pfcrt (n = 297)
M74I
36
12.12
N75E
K76T
47
15.82
pfmdr1 (n = 262)
N86Y
7
2.67
E130K
0
0.00
Y184F
208
79.39
S1034C
N1042D
2
0.76
V1109I
D1246Y
3
1.15