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Table 3 Isolation and characterization studies on medicinal plants used for management of TB in East Africa

From: Ethnobotany, ethnopharmacology, and phytochemistry of traditional medicinal plants used in the management of symptoms of tuberculosis in East Africa: a systematic review

Plant

Pure compounds with antitubercular activity

Chemical class

MIC of pure compounds (μg/ml)

Author(s)

Zanthoxylum leprieurii

2-hydroxy-1, 3-dimethoxy-10-methyl-9-acridone (1), 1-hydroxy-3-methoxy-10-methyl-9-acridone (2), 3-hydroxy-1, 5, 6-trimethoxy-9-acridone (3)

Acridone alkaloids

1.5 (1), 0.2 (2), 0.4 (3); tested against H37Rv

[5]

Warburgia ugandensis Sprague

Muzigadial (4), muzigadiolide (5), linoleic acid (6)

Sesquiterpenes

64 (4), 128 (5), 16 (6); tested against M. smegmatis

[58, 85]

Tetradenia riparia

15- sandaracopimaradiene-7α, 18-dio1 (7)

Diterpenediol

25–100

[37]

  1. MIC minimum inhibitory concentration. No toxicity studies of the pure compounds were conducted.
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Tropical Medicine and Health

ISSN: 1349-4147

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